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Protocol - Post-acute Withdrawal Signs and Symptoms

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Description

The Symptom Checklist-90 (SCL-90) is a 90-item questionnaire used to assess psychological problems.

Specific Instructions

The PhenX Substance Use and Recovery Working Group (WG) notes that investigators may want to adapt the Symptom Checklist-90 (SCL-90) for inquiry into specific drugs (e.g., opioids, cannabis) and timeframes (e.g., past 90 days, past year). Although the SCL-90 was designed to assess psychological problems generally, there are many items that reflect post-acute withdrawal signs and symptoms, so researchers may consider using some of the subscales to assess for such signs and symptoms.

The Anxiety Subscale from the SCL-90 is included here and in the Anxiety Disorders Symptoms - Adult measure. Therefore, if both protocols are selected, the Anxiety Subscale should be included only one time.

Protocols may include terms and language that could be triggering to respondents. Investigators are encouraged to have resources in place to help respondents cope with triggers as needed.

Terminology related to substances, substance use, and recovery is fluid. Updates in protocol language may be appropriate based on circumstance. Suggestions for revision have been offered to update answer responses or other components of the questionnaires to account for the constantly changing landscape. These suggestions have not been tested or validated in research studies but may be considered by investigators to enhance relevance.

Availability

This protocol has limited availability; permission required for use.

Protocol

Symptom Checklist-90 (SCL-90)

The Medical Cannabis Use, Polysubstance Use, and Recovery Working Group recommends that investigators collect 65 items from 6 subscales of the SCL-90 specific to post-acute withdrawal assessment (somatization, obsessive-compulsive, depression, anxiety, anger-hostility, and phobic-anxiety).

The SCL-90 is a proprietary instrument, and administration requires a licensing agreement from The Gottman Institute, Inc. Copyright © 2000–2009 by Dr. John M. Gottman and Dr. Julie Schwartz Gottman.

Contact Information:
Dr. John M. Gottman and Dr. Julie Schwartz Gottman, The Gottman Institute, Inc.
Website: https://www.gottman.com/permission-request-form/

Personnel and Training Required
None
Equipment Needs
None
Requirements
Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual Yes
Mode of Administration

Self-administered questionnaire

Lifestage

Adult, Senior

Participants

Adults, ages 20 and older

Selection Rationale

Because there are currently no diagnostic criteria for post-acute withdrawal symptoms (PAWS), the Medical Cannabis Use, Polysubstance Use, and Recovery Working Group selected the Symptom Checklist-90 (SCL-90). It is a validated scale for symptoms that are typical for PAWS that is freely available.

Language

English, Finnish

Standards
StandardNameIDSource
Derived Variables

None

Process and Review

Not Applicable

Protocol Name from Source

Symptom Checklist-90 (SCL-90)

Source

Derogatis, L. R., Lipman, R. S., & Covi, L. (1973). SCL-90: An outpatient psychiatric rating scale—Preliminary report. Psychopharmacology Bulletin, 9, 13–28.

University of Wisconsin-Madison Addition Research Center. (2024, June 19). Symptom Checklist-90 (SCL90).
https://arc.psych.wisc.edu/self-report/symptom-checklist-90-scl90/

General References

Derogatis, L. R., Rickels, K., & Rock, A. F. (1976). The SCL-90 and the MMPI: A step in the validation of a new self-report scale. British Journal of Psychiatry, 128(3), 280–289.

Dinning, W. D., & Evans, R. G. (1977). Discriminant and convergent validity of the SCL-90 in psychiatric inpatients. Journal of Personality Assessment, 41(3), 304–310.

Holi, M. M., Sammallahti, P. R., & Aalberg, V. A. (1998). A Finnish validation study of the SCL-90. Acta Psychiatrica Scandinavica, 97(1), 42–46.

Masal, E., Koç, M., Çolak, T. S., & Takunyaci, M. (2013). Analyzing the psychological symptoms of students in undergraduate program in elementary mathematics teaching. Educational Research and Reviews, 8(14), 1117.

Protocol ID

511701

Variables
Export Variables
Variable Name Variable IDVariable DescriptiondbGaP Mapping
Assessment of Substance Use and Substance Use Disorders
Measure Name

Post-acute withdrawal signs and symptoms

Release Date

January 30, 2025

Definition

Post-acute withdrawal signs include psycho-biological signs and symptoms that persist in the absence of substance exposure during the early weeks, months, and sometimes years of remission caused by chronic exposure to toxic substances (e.g., alcohol, meth/amphetamine, heroin).

Purpose

Adequate assessment and medical- or self-management of post-acute withdrawal signs and symptoms are necessary to help prevent relapse and substance use disorder (SUD) recurrence. Salutary changes in withdrawal signs and symptoms represent psychobiological healing that helps build recovery resilience.

Keywords

Somatization, obsessive-compulsive, depression, anger-hostility, phobic-anxiety, alcohol withdrawal

Measure Protocols
Protocol ID Protocol Name
511701 Post-acute Withdrawal Signs and Symptoms
511702 Post-acute withdrawal signs and symptoms - Craving