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Protocol - Post-acute withdrawal signs and symptoms - Craving

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Description

The Penn Alcohol Craving Scale (PACS) is a five-item, self-report measure that includes questions about the frequency, intensity, and duration of craving alcohol; the ability to resist drinking alcohol; and an overall rating of craving for alcohol for the previous week.

Specific Instructions

The PhenX Substance Use and Recovery Working Group (WG) recommends the scale could be adapted to other substances and timeframes. 

Protocols may include terms and language that could be triggering to respondents. Investigators are encouraged to have resources in place to help respondents cope with triggers as needed.

Terminology related to substances, substance use, and recovery is fluid. Updates in protocol language may be appropriate based on circumstance. Suggestions for revision have been offered to update answer responses or other components of the questionnaires to account for the constantly changing landscape. These suggestions have not been tested or validated in research studies but may be considered by investigators to enhance relevance.

Availability

This protocol is freely available; permission not required for use.

Protocol

Penn Alcohol Craving Scale (PACS)

Please read each item carefully and circle the number that best describes your craving during the past week.

1. During the past week how often have you thought about drinking or about how good a drink would make you feel?

0[ ]Never (0 times during the past week)

1[ ]Rarely (1 to 2 times during the past week)

2[ ]Occasionally (3 to 4 times during the past week)

3[ ]Sometimes (5 to 10 times during the past week or 1 to 2 times per day)

4[ ]Often (11 to 20 times during the past week or 2 to 3 times per day)

5[ ]Most of the time (20 to 40 times during the past week or 3 to 6 times per day)

6[ ]Nearly all the time (more than 40 times during the past week or more than 6 times per day)

2. At its most severe point, how strong was your craving during the past week?

0[ ]None at all

1[ ]Slight, that is a very mild urge

2[ ]Mild urge

3[ ]Moderate urge

4[ ]Strong urge, but easily controlled

5[ ]Strong urge and difficult to control

6[ ]Strong urge and would have drunk alcohol if it were available

3. During the past week how much time have you spent thinking about drinking or about how good a drink would make you feel?

0[ ]None at all

1[ ]Less than 20 minutes

2[ ]21 to 45 minutes

3[ ]46 to 90 minutes

4[ ]90 minutes to 3 hours

5[ ]Between 3 to 6 hours

6[ ]More than 6 hours

4. During the past week how difficult would it have been to resist taking a drink if you had known a bottle were in your house?

0[ ]Not difficult at all

1[ ]Very mildly difficult

2[ ]Mildly difficult

3[ ]Moderately difficult

4[ ]Very difficult

5[ ]Extremely difficult

6[ ]Would not be able to resist

5. Keeping in mind your responses to the previous questions, please rate your overall average alcohol craving for the past week.

0[ ]Never thought about drinking and never had the urge to drink

1[ ]Rarely thought about drinking and rarely had the urge to drink

2[ ]Occasionally thought about drinking and occasionally had the urge to drink

3[ ]Sometimes thought about drinking and sometimes had the urge to drink

4[ ]Often thought about drinking and often had the urge to drink

5[ ]Thought about drinking most of the time and had the urge to drink most of the time

6[ ]Thought about drinking nearly all of the time and had the urge to drink nearly all of the time

Scoring Instructions

Each response is scored from 0 to 6. Items are added together to yield a total score ranging from 0 to 30, with higher scores indicating greater levels of alcohol craving. Craving and other alcohol use disorder symptoms were scored categorically as absent, subclinical, or present. An average item score below 3 (total < 15) indicates mild craving and was categorized as symptom absent. An average item score below 4 (total 15–20) indicates moderate craving and was categorized as subclinical. An average item score above 4 (total > 20) indicates strong craving and was categorized as symptom present.

Personnel and Training Required

None


Equipment Needs

None


Requirements
Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Self-administered questionnaire

Lifestage

Adult, Senior

Participants

Adults, ages 20 and older

Selection Rationale

The Penn Alcohol Craving Scale (PACS) is a well-established, valid, and reliable measure of alcohol craving and can help predict which individuals are at risk for subsequent relapse.

Language

English

Standards
StandardNameIDSource
Derived Variables

None

Process and Review

Not Applicable

Protocol Name from Source

Penn Alcohol Craving Scale (PACS)

Source

Flannery, B. A., Volpicelli, J. R., & Pettinati, H. M. (1999). Psychometric properties of the Penn Alcohol Craving Scale. Alcoholism, Clinical and Experimental Research, 23(8), 1289–1295.

General References

Bahji, A., Crockford, D., & El-Guebaly, N. (2022). Management of post-acute alcohol withdrawal: A mixed-studies scoping review.?Journal of Studies on Alcohol and Drugs,?83(4), 470–479. https://doi.org/10.15288/jsad.2022.83.470


Murphy, C. M., Stojek, M. K., Few, L. R., Rothbaum, A. O., & Mackillop, J. (2014). Craving as an alcohol use disorder symptom in DSM-5: An empirical examination in a treatment-seeking sample. Experimental and Clinical Psychopharmacology, 22(1), 43–49. https://doi.org/10.1037/a0034535

Protocol ID

511702

Variables
Export Variables
Variable Name Variable IDVariable DescriptiondbGaP Mapping
Assessment of Substance Use and Substance Use Disorders
Measure Name

Post-acute withdrawal signs and symptoms

Release Date

January 30, 2025

Definition

Post-acute withdrawal signs include psycho-biological signs and symptoms that persist in the absence of substance exposure during the early weeks, months, and sometimes years of remission caused by chronic exposure to toxic substances (e.g., alcohol, meth/amphetamine, heroin).

Purpose

Adequate assessment and medical- or self-management of post-acute withdrawal signs and symptoms are necessary to help prevent relapse and substance use disorder (SUD) recurrence. Salutary changes in withdrawal signs and symptoms represent psychobiological healing that helps build recovery resilience.

Keywords

addiction, addictive behaviors, alcohol use, sobriety, cravings, Penn Alcohol Craving Scale, PACS, relapse, alcohol craving, substance use, substance use disorder, SUD, alcohol use disorder, AUD, addiction, withdrawal

Measure Protocols
Protocol ID Protocol Name
511701 Post-acute Withdrawal Signs and Symptoms
511702 Post-acute withdrawal signs and symptoms - Craving