Substance Use and Recovery Working Group (2025)
In September 2023, the National Institute on Drug Abuse (NIDA) funded an administrative supplement to PhenX to identify measurement protocols for substance use (medical cannabis and polysubstance use) and substance use recovery for inclusion in the PhenX (consensus measures for Phenotypes and eXposures) Toolkit (www.phenxtoolkit.org). Secondary areas of focus included identification of updates to language and imagery to address stigma (e.g., “abuse”).
The PhenX Substance Use and Recovery Working Group added 30 protocols to the existing Substance Use, Use Disorders, and Recovery (SUR) collections and was composed of nine scientists with expertise in the designated areas:
- Yuh-Pey Anne Buu, PhD (Co-chair), University of Texas Health Science Center at Houston
- John Kelly, PhD (Co-chair), Harvard Medical School
- Amanda Bunting, PhD, New York University, Langone Health
- Christian Hopfer, MD, University of Colorado Denver
- Ryan McNeil, PhD, Yale University
- Johannes Thrul, PhD, Johns Hopkins University
- Denis Vidot, PhD, University of Miami
- Corrie Vilsaint, PhD, MGH Recovery Research Institute
- Sarah Zemore, PhD, Alcohol Research Group
Protocols added to the PhenX Toolkit
- General Cannabis Use
- Cannabis Products, Types, and Modes of Use
- Assessment of Cannabis Use Disorder
- Sources of Cannabis
- Motives for Using Medical Cannabis
- Medical Cannabis Card Status
- Medical Cannabis Provider-Patient Communication
- Biochemical Validation of Cannabis Consumption
- Co-use of Opioids with Other Drugs and Overdose Risk
- Alcohol and Cannabis Simultaneous Use
- Patterns of Substance Use – Alcohol and/or Drug Use
- Patterns of Substance Use – Calendar-based Method for Detailed Cannabis Use
- Polysubstance Use Frequency – Past Year
- Post-acute withdrawal signs and symptoms
- Post-acute withdrawal signs and symptoms – Craving
- Motives – Alcohol, Tobacco, and Other Substances – Cannabis
- Expectancies for Medical Cannabis Use
- Social Relationship Quality
- Brief Assessment of Social Network Characteristics
- Comprehensive Interviewer-administered Assessment of Social Network Characteristics
- Substance Use Goal
- Recovery Identification
- Multidimensional Assessment of Recovery Capital
- Unidimensional Assessment of Recovery Capital
- Use of Treatment and Recovery Support Services
- Mutual-help Group Involvement and Treatment Attendance
- 12-Step Group Participation
- Future Service Needs – Self-Help Involvement
- Client Satisfaction
- Happiness with Recovery
PhenX Substance Use and Recovery Working Group Responsibilities
The goals of the PhenX Substance Use and Recovery WG were to:
- Identify and review well-established measurement protocols and instruments currently in use in the field
- Examine Substance Use and Recovery - related measurement protocols in the PhenX Toolkit to ensure that newly selected protocols complement existing Toolkit content
- Select up to 18 preliminary protocols to share with the research community and get feedback (community outreach)
- Suggest groups in the research community for the community outreach efforts
- Consider feedback from community outreach when deciding the high-priority Substance Use and Recovery protocols to be included in the Toolkit
- Present recommended protocols to the PhenX Steering Committee (SC) for approval
PhenX Measures for Substance Use and Recovery Senior Management Team
| National Institute on Drug Abuse (NIDA) | |
|---|---|
|
Tamara Haegerich, PhD Project Scientist |
|
| National Human Genome Research Institute (NHGRI) | |
|
Jyoti Dayal, MS PhenX Project Scientist |
Weini Ogbagiorgis, BS PhenX Project Analyst |
| RTI International | |
|
Carol M. Hamilton, PhD Principal Investigator |
Cataia Ives, MS WG Supervisor |
|
Tabitha Hendershot, BA Co-Investigator |
Christine Hill, MPH Working Group Manager |
|
Wayne Huggins, PhD Co-Investigator |
Lisa Gehtland, MD Consensus Coordinator |
|
Cindy Changar Project Manager |
|